#	Package	Description	Downloads (30 days)
1	boto3	The AWS SDK for Python	3.7B
2	requests	Python HTTP for Humans.	1.8B
3	cryptography	cryptography is a package which provides cryptographic recipes and primitives to Python developers.	1.5B
4	cffi	Foreign Function Interface for Python calling C code.	1.3B
5	pygments	Pygments is a syntax highlighting package written in Python.	1.3B
6	pyyaml	YAML parser and emitter for Python	1.2B
7	python-dateutil	Extensions to the standard Python datetime module	1.2B
8	aiobotocore	Async client for aws services using botocore and aiohttp	1.2B
9	numpy	Fundamental package for array computing in Python	1.1B
10	pycparser	C parser in Python	1.1B
11	pydantic	Data validation using Python type hints	1.1B
12	pytest	pytest: simple powerful testing with Python	1.1B
13	click	Composable command line interface toolkit	1.1B
14	anyio	High-level concurrency and networking framework on top of asyncio or Trio	1.0B
15	pydantic-core	Core functionality for Pydantic validation and serialization	1.0B
16	grpcio-status	Status proto mapping for gRPC	951M
17	h11	A pure-Python, bring-your-own-I/O implementation of HTTP/1.1	895M
18	fsspec	File-system specification	879M
19	annotated-types	Reusable constraint types to use with typing.Annotated	871M
20	protobuf		868M
21	markupsafe	Safely add untrusted strings to HTML/XML markup.	797M
22	httpx	The next generation HTTP client.	797M
23	httpcore	A minimal low-level HTTP client.	784M
24	typing-inspection	Runtime typing introspection tools	783M
25	pandas	Powerful data structures for data analysis, time series, and statistics	769M
26	pathspec	Utility library for gitignore style pattern matching of file paths.	743M
27	python-dotenv	Read key-value pairs from a .env file and set them as environment variables	740M
28	jinja2	A very fast and expressive template engine.	719M
29	pyjwt	JSON Web Token implementation in Python	716M
30	s3fs	Convenient Filesystem interface over S3	704M
31	litellm	Library to easily interface with LLM API providers	683M
32	tqdm	Fast, Extensible Progress Meter	649M
33	aiohttp	Async http client/server framework (asyncio)	644M
34	yarl	Yet another URL library	621M
35	rich	Render rich text, tables, progress bars, syntax highlighting, markdown and more to the terminal	614M
36	markdown-it-py	Python port of markdown-it. Markdown parsing, done right!	614M
37	rpds-py	Python bindings to Rust's persistent data structures (rpds)	614M
38	uvicorn	The lightning-fast ASGI server.	610M
39	starlette	The little ASGI library that shines.	606M
40	jsonschema	An implementation of JSON Schema validation for Python	597M
41	multidict	multidict implementation	594M
42	google-auth	Google Authentication Library	590M
43	propcache	Accelerated property cache	587M
44	pyasn1	Pure-Python implementation of ASN.1 types and DER/BER/CER codecs (X.208)	571M
45	fastapi	FastAPI framework, high performance, easy to learn, fast to code, ready for production	569M
46	aiohappyeyeballs	Happy Eyeballs for asyncio	561M
47	frozenlist	A list-like structure which implements collections.abc.MutableSequence	554M
48	pytz	World timezone definitions, modern and historical	552M
49	mdurl	Markdown URL utilities	548M
50	pillow	Python Imaging Library (fork)	547M
51	referencing	JSON Referencing + Python	545M
52	websockets	An implementation of the WebSocket Protocol (RFC 6455 & 7692)	543M
53	opentelemetry-semantic-conventions	OpenTelemetry Semantic Conventions	543M
54	trove-classifiers	Canonical source for classifiers on PyPI (pypi.org).	540M
55	jsonschema-specifications	The JSON Schema meta-schemas and vocabularies, exposed as a Registry	540M
56	aiosignal	aiosignal: a list of registered asynchronous callbacks	537M
57	opentelemetry-sdk	OpenTelemetry Python SDK	522M
58	googleapis-common-protos	Common protobufs used in Google APIs	514M
59	tzdata	Provider of IANA time zone data	505M
60	wrapt	Module for decorators, wrappers and monkey patching.	496M
61	sniffio	Sniff out which async library your code is running under	487M
62	hatchling	Modern, extensible Python build backend	484M
63	google-api-core	Google API client core library	482M
64	greenlet	Lightweight in-process concurrent programming	476M
65	opentelemetry-api	OpenTelemetry Python API	464M
66	pyasn1-modules	A collection of ASN.1-based protocols modules	462M
67	annotated-doc	Document parameters, class attributes, return types, and variables inline, with Annotated.	456M
68	pydantic-settings	Settings management using Pydantic	453M
69	scipy	Fundamental algorithms for scientific computing in Python	449M
70	grpcio	HTTP/2-based RPC framework	446M
71	textual	Modern Text User Interface framework	444M
72	huggingface-hub	Client library to download and publish models, datasets and other repos on the huggingface.co hub	442M
73	regex	Alternative regular expression module, to replace re.	438M
74	pyarrow	Python library for Apache Arrow	433M
75	beautifulsoup4	Screen-scraping library	432M
76	tenacity	Retry code until it succeeds	429M
77	soupsieve	A modern CSS selector implementation for Beautiful Soup.	429M
78	sqlalchemy	Database Abstraction Library	423M
79	lxml	Powerful and Pythonic XML processing library combining libxml2/libxslt with the ElementTree API.	417M
80	python-multipart	A streaming multipart parser for Python	412M
81	opentelemetry-exporter-otlp-proto-http	OpenTelemetry Collector Protobuf over HTTP Exporter	410M
82	opentelemetry-proto	OpenTelemetry Python Proto	406M
83	openai	The official Python library for the openai API	398M
84	opentelemetry-instrumentation	Instrumentation Tools & Auto Instrumentation for OpenTelemetry Python	394M
85	jiter	Fast iterable JSON parser.	393M
86	psutil	Cross-platform lib for process and system monitoring.	388M
87	shellingham	Tool to Detect Surrounding Shell	382M
88	requests-oauthlib	OAuthlib authentication support for Requests.	370M
89	typer	Typer, build great CLIs. Easy to code. Based on Python type hints.	369M
90	watchfiles	Simple, modern and high performance file watching and code reload in python.	357M
91	more-itertools	More routines for operating on iterables, beyond itertools	351M
92	openpyxl	A Python library to read/write Excel 2010 xlsx/xlsm files	351M
93	editables	Editable installations	350M
94	cachetools	Extensible memoizing collections and decorators	345M
95	proto-plus	Beautiful, Pythonic protocol buffers	344M
96	et-xmlfile	An implementation of lxml.xmlfile for the standard library	343M
97	opentelemetry-exporter-otlp-proto-common	OpenTelemetry Protobuf encoding	341M
98	awscli	Universal Command Line Environment for AWS.	340M
99	coverage	Code coverage measurement for Python	336M
100	oauthlib	A generic, spec-compliant, thorough implementation of the OAuth request-signing logic	333M