#	Package	Description	Downloads (30 days)
1	boto3	The AWS SDK for Python	3.6B
2	requests	Python HTTP for Humans.	1.7B
3	cryptography	cryptography is a package which provides cryptographic recipes and primitives to Python developers.	1.3B
4	aiobotocore	Async client for aws services using botocore and aiohttp	1.3B
5	pygments	Pygments is a syntax highlighting package written in Python.	1.2B
6	python-dateutil	Extensions to the standard Python datetime module	1.1B
7	pyyaml	YAML parser and emitter for Python	1.1B
8	numpy	Fundamental package for array computing in Python	1.1B
9	cffi	Foreign Function Interface for Python calling C code.	1.1B
10	pydantic	Data validation using Python type hints	1.1B
11	pytest	pytest: simple powerful testing with Python	1.0B
12	click	Composable command line interface toolkit	1.0B
13	pycparser	C parser in Python	994M
14	grpcio-status	Status proto mapping for gRPC	952M
15	pydantic-core	Core functionality for Pydantic validation and serialization	938M
16	anyio	High-level concurrency and networking framework on top of asyncio or Trio	936M
17	protobuf		857M
18	h11	A pure-Python, bring-your-own-I/O implementation of HTTP/1.1	832M
19	fsspec	File-system specification	832M
20	annotated-types	Reusable constraint types to use with typing.Annotated	777M
21	pandas	Powerful data structures for data analysis, time series, and statistics	770M
22	s3fs	Convenient Filesystem interface over S3	762M
23	markupsafe	Safely add untrusted strings to HTML/XML markup.	745M
24	httpx	The next generation HTTP client.	745M
25	httpcore	A minimal low-level HTTP client.	728M
26	typing-inspection	Runtime typing introspection tools	715M
27	jinja2	A very fast and expressive template engine.	676M
28	python-dotenv	Read key-value pairs from a .env file and set them as environment variables	675M
29	pathspec	Utility library for gitignore style pattern matching of file paths.	653M
30	pyjwt	JSON Web Token implementation in Python	640M
31	litellm	Library to easily interface with LLM API providers	633M
32	aiohttp	Async http client/server framework (asyncio)	632M
33	rich	Render rich text, tables, progress bars, syntax highlighting, markdown and more to the terminal	621M
34	markdown-it-py	Python port of markdown-it. Markdown parsing, done right!	609M
35	yarl	Yet another URL library	608M
36	tqdm	Fast, Extensible Progress Meter	607M
37	propcache	Accelerated property cache	582M
38	rpds-py	Python bindings to Rust's persistent data structures (rpds)	577M
39	multidict	multidict implementation	575M
40	google-auth	Google Authentication Library	560M
41	jsonschema	An implementation of JSON Schema validation for Python	558M
42	starlette	The little ASGI library that shines.	552M
43	mdurl	Markdown URL utilities	551M
44	pytz	World timezone definitions, modern and historical	548M
45	pyasn1	Pure-Python implementation of ASN.1 types and DER/BER/CER codecs (X.208)	544M
46	aiohappyeyeballs	Happy Eyeballs for asyncio	543M
47	frozenlist	A list-like structure which implements collections.abc.MutableSequence	540M
48	uvicorn	The lightning-fast ASGI server.	525M
49	aiosignal	aiosignal: a list of registered asynchronous callbacks	523M
50	opentelemetry-sdk	OpenTelemetry Python SDK	522M
51	sglang	SGLang is a fast serving framework for large language models and vision language models.	507M
52	fastapi	FastAPI framework, high performance, easy to learn, fast to code, ready for production	506M
53	trove-classifiers	Canonical source for classifiers on PyPI (pypi.org).	506M
54	referencing	JSON Referencing + Python	504M
55	googleapis-common-protos	Common protobufs used in Google APIs	501M
56	tzdata	Provider of IANA time zone data	500M
57	jsonschema-specifications	The JSON Schema meta-schemas and vocabularies, exposed as a Registry	499M
58	pillow	Python Imaging Library (fork)	494M
59	opentelemetry-semantic-conventions	OpenTelemetry Semantic Conventions	489M
60	google-api-core	Google API client core library	484M
61	annotated-doc	Document parameters, class attributes, return types, and variables inline, with Annotated.	471M
62	wrapt	Module for decorators, wrappers and monkey patching.	464M
63	pyasn1-modules	A collection of ASN.1-based protocols modules	460M
64	greenlet	Lightweight in-process concurrent programming	447M
65	grpcio	HTTP/2-based RPC framework	443M
66	sniffio	Sniff out which async library your code is running under	442M
67	typer	Typer, build great CLIs. Easy to code. Based on Python type hints.	440M
68	tenacity	Retry code until it succeeds	435M
69	websockets	An implementation of the WebSocket Protocol (RFC 6455 & 7692)	430M
70	opentelemetry-api	OpenTelemetry Python API	428M
71	scipy	Fundamental algorithms for scientific computing in Python	427M
72	shellingham	Tool to Detect Surrounding Shell	425M
73	pyarrow	Python library for Apache Arrow	418M
74	hatchling	Modern, extensible Python build backend	417M
75	beautifulsoup4	Screen-scraping library	414M
76	sqlalchemy	Database Abstraction Library	408M
77	huggingface-hub	Client library to download and publish models, datasets and other repos on the huggingface.co hub	408M
78	soupsieve	A modern CSS selector implementation for Beautiful Soup.	407M
79	regex	Alternative regular expression module, to replace re.	400M
80	opentelemetry-exporter-otlp-proto-http	OpenTelemetry Collector Protobuf over HTTP Exporter	398M
81	pydantic-settings	Settings management using Pydantic	394M
82	opentelemetry-proto	OpenTelemetry Python Proto	388M
83	psutil	Cross-platform lib for process and system monitoring.	383M
84	lxml	Powerful and Pythonic XML processing library combining libxml2/libxslt with the ElementTree API.	375M
85	requests-oauthlib	OAuthlib authentication support for Requests.	374M
86	python-multipart	A streaming multipart parser for Python	372M
87	openai	The official Python library for the openai API	369M
88	textual	Modern Text User Interface framework	365M
89	more-itertools	More routines for operating on iterables, beyond itertools	351M
90	jiter	Fast iterable JSON parser.	350M
91	cachetools	Extensible memoizing collections and decorators	340M
92	watchfiles	Simple, modern and high performance file watching and code reload in python.	335M
93	langchain	Building applications with LLMs through composability	330M
94	oauthlib	A generic, spec-compliant, thorough implementation of the OAuth request-signing logic	329M
95	opentelemetry-instrumentation	Instrumentation Tools & Auto Instrumentation for OpenTelemetry Python	325M
96	awscli	Universal Command Line Environment for AWS.	323M
97	proto-plus	Beautiful, Pythonic protocol buffers	319M
98	openpyxl	A Python library to read/write Excel 2010 xlsx/xlsm files	318M
99	opentelemetry-exporter-otlp-proto-common	OpenTelemetry Protobuf encoding	317M
100	et-xmlfile	An implementation of lxml.xmlfile for the standard library	313M